Abstract: The population hybridization was conducted by using clams Ruditapes plippinarum of two shell color strains ocean red(R), zebra(Z) strains in October of 2007. The experiments was consisted of RR (R♀R♂), ZZ (Z♀Z♂), RZ(R♀Z♂) and ZR (Z♀R♂) groups. Results showed that difference of shell length, weight and fecundity of parents were significant between two shell color strains (P＜0.05). There were no difference on egg-diameters, fertilization rates and sizes of D larvae among each experimental groups (P＞0.05). The hatching rates in hybrid groups were higher than in control groups (P＜0.05). At the planktonic stage, survival heterosis was obvious instead of growth heterosis for larvae tested. Survival heterosis were (10.301.92)% and (16.301.04)%, respectively for RZ and ZR, and growth heterosis for RZ, ZR were (1.630.81)% and (2.580.67)%. Growth rates for RZ, ZR were (8.640.32) and (8.670.31) md-1, respectively (P＜0.05). At indoor rearing stage, obvious growth and survival heterosis were found. The growth heterosis of RZ, ZR were (11.252.98)% and (20.312.10)%, the growth rates were (9.881.45) and (10.791.32) md-1, and the survival heterosis were (40.859.90)% and (57.0811.98)%, respectively. There was no significant difference of survival heterosis between RR, and ZZ (P0.05).